Figure 2.
Mendelian randomization estimates (odds ratio with 95% CI per 10 mmHg increase in genetically predicted systolic blood pressure) from the inverse variance weighted method. SNP indicates single nucleotide polymorphism; OR, odd ratios; SBP, systolic blood pressure; DBP, diastolic blood pressure. * 242 SNPs associated with both SBP and DBP (p < 5 × 10−4), identified in a BP GWAS meta-analysis study [17]. † 120 SNPs associated with SBP (p < 5 × 10−4) but not associated with DBP. ‡ 63 SNPs associated with SBP (p < 5 × 10−8) but not associated with DBP (p > 5 × 10−4).