Table 1.
Genome-wide association studies included in this MR study.
| Traits | Consortium/Cohort | Sample Size (Cases) | Population | Reference |
|---|---|---|---|---|
| Systolic blood pressure | Evangelou E (2018) | 757,601 | European | [17] |
| Systolic blood pressure | Neale Lab (2017) | 317,756 | European | [18] |
| Diastolic blood pressure | Evangelou E (2018) | 757,601 | European | [17] |
| Diastolic blood pressure | Neale Lab (2017) | 317,756 | European | [18] |
| Coronary artery disease | CARDIoGRAMplusC4D | 184,305 (60,801) | 77% European | [19] |
| Myocardial infarction | CARDIoGRAMplusC4D | 171,875 (43,676) | 77% European | [19] |
| Stroke | MEGASTROKE | 446,696 (40,585) | European | [20] |
| Heart failure | FinnGen | 208,178 (13,087) | European | [21] |
| Atrial fibrillation | Nielsen JB (2018) | 1,030,836 (60,620) | European | [22] |
| Chronic kidney disease | CKDGen | 117,165 (12,385) | European | [23] |
| Type 2 diabetes | Xue A (2018) | 655,666 (61,714) | European | [24] |