Table 1.
Study and patient characteristics.
| Reference | N = Total Number of Patients | Patient Selection Method | % Incidence Rate of Brain Metastases | Median Time between Diagnoses in Months (range) a | Prostate Cancer Type b | ||
|---|---|---|---|---|---|---|---|
| CSPC | CRPC | Not Specified | |||||
| Myint ZW 2021 [4] | 187 | AD | 1.26 | 187 | |||
| Boxley PJ 2021 [5] | 29 | AD | 0.44 | 4 | 25 | ||
| Bhambhvani HP 2020 [11] | 31 | RC | 81 (3–195) | 31 | |||
| Nguyen T 2020 [12] | 21 | RC | 21 | ||||
| Ganau M 2020 [40] | 19 | RC | 10 | 9 | |||
| Ormond DR 2019 [46] | 21 | AD | 90 (0–312) | 1 | 20 | ||
| Zhao F 2019 [44] | 126 | AD | 0.76 | 126 | |||
| Kanyılmaz G 2019 [13] | 10 | RC | 10 | ||||
| Hatzoglou V 2014 [38] | 21 | RC | 0.16 | 46 | 21 | ||
| Bartscht T 2014 [30] | 18 | RC | 18 | ||||
| Gzell CE 2013 [39] | 4 | CS | 1 | 3 | |||
| Caffo O 2013 [7] | 9 | AD | 36 (0–111) | 9 | |||
| Caffo O 2012 [47] | 31 | AD | 3.29 | 44 (6–173) | 31 | ||
| Guedes B 2011 [37] | 6 | CS | 3 | 3 | |||
| Lawton A 2010 [45] | 10 | RC | 8.06 | 40 (21–164) | 10 | ||
| Flannery T 2010 [31] | 10 | RC | 1.01 | 36 (12–180) | 1 | 9 | |
| Lin C 2008 [10] | 4 | CS | 4 | ||||
| Kim SH 2008 [32] | 5 | AD | 82 | 5 | |||
| Salvati M 2005 [9] | 13 | RC | 45 (mean) | 13 | |||
| Tremont-Lukats IW 2003 [14] | 103 | RC | 0.63 | 103 | |||
| McCutcheon IE 1999 [34] | 38 | RC | 0.48 | 29 (0–84) | 38 | ||
| Nussbaum ER 1996 [36] | 11 | RC | 22 | 11 | |||
| Chung TS 1986 [42] | 8 | RC | 0.61 | 6 (0–73) | 2 | 6 | |
| Taylor HG 1984 [33] | 14 | AR | 4.13 | 5 | 9 | ||
| Castaldo JE 1983 [43] | 8 | AR | 4.23 | 8 | |||
| Sarma DP 1983 [35] | 4 | AR | 3.31 | 3 | 1 | ||
| Catane R 1976 [41] | 5 | AR | 4.40 | 61 (mean) | 5 | ||
| Overall Median | 13 | N/A | 1.14 | 42 | N/A | N/A | N/A |
AD: administrative database review; RC: retrospective chart review; CS: case series; AR: autopsy review; CSPC: castration-sensitive prostate cancer; CRPC: castration-resistant prostate cancer; and N/A: not applicable. Cells were left blank when this information was not reported in the article. a Time between prostate cancer diagnosis and brain metastasis diagnosis. b Prostate cancer type at time of brain metastasis diagnosis.