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. 2022 Jul 10;11(14):2160. doi: 10.3390/cells11142160

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Visualization of the top 200 DEGs involved in histone modifications. (A) top panel: relation between histone modifications and top 40 DEGs among top 200 DEGs suppressed by TP-472 treatment (down). Lower panel: Top 10 altered epigenetic terms from top 200 down DEGs upon TP-472 treatment, (B) Top panel: the relation between histone modifications and top 40 DEGs among top 200 DEGs induced by TP-472 treatment (up). Lower panel: top 10 altered epigenetic terms from top 200 up DEGs upon TP-472 treatment. Note: Arabic numerals are the index for histone modifications.