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Visualization of the top 200 DEGs involved in miRNA regulation. (A) The relation between top 20 down/up miRNAs and top 200 up/down DEGs, (B) Model showing that TP-472 treatment activates apoptosis, induces cell cycle arrest, induces miRNA-mediated gene regulation, and reprograms pro-oncogenic epigenome in uLMS cells. Note: Arabic numerals are the index for histone modifications. Figure 9B was created using BioRender software.
