Table 2.
AGREE II assessment results and domain scores for the four included CPGs *.
| Source CPGs/AGREE II Domains Scores (%) | ACRC 2018 [35] |
NZ 2016 [36] |
NICE 2017 [37] |
SIGN 2019 [38] |
|---|---|---|---|---|
|
Domain 1. Scope and Purpose Items 1–3: Objectives; health question(s); population (patients, public, etc.) |
99% | 93% | 96% | 97% |
|
Domain 2. Stakeholder Involvement Items 4–6: Group membership; target population preferences and views; target users |
99% | 71% | 72% | 79% |
|
Domain 3. Rigor of development Items 7–14: Search methods; evidence selection criteria; strengths and limitations of the evidence; formulation of recommendations; consideration of benefits and harms; link between recommendations and evidence; external review; updating procedure. |
84% | 86% | 93% | 85% |
|
Domain 4. Clarity and presentation Items 15–17: Specific and unambiguous recommendations; management options; identifiable key recommendations |
93% | 94% | 97% | 93% |
|
Domain 5. Applicability Items 18–21: Facilitators and barriers to application; implementation advice/tools; resource implications; monitoring/auditing criteria |
92% | 54% | 89% | 85% |
|
Domain 6. Editorial independence Items 22, 23: Funding body; competing interests |
92% | 69% | 92% | 92% |
|
Overall Assessment 1 (Overall quality) |
92% | 88% | 96% | 92% |
|
Overall Assessment 2 (Recommend the CPG for use by four appraisers) |
Yes—3, Yes with modifications—1, No—0 | Yes—4, Yes with modifications—0, No—0 | Yes—2, Yes with modifications—2, No—0 | Yes—2, Yes with modifications—2, No—0 |
* AGREE II (Appraisal of Guidelines for REsearch and Evaluation Version II Instrument); Australian Autism CRC (ACRC); Ministry of Health New Zealand (NZ); National Institute for Health and Care Excellence (NICE); Scottish Intercollegiate Guidelines Network, Healthcare Improvement Scotland (SIGN-HIS). This AGREE II domain scores table is a standard template with a constant set of attributes that have been reported in most similar reports of AGREE II assessment of guidelines (example: Alhasan, K.A., Al Khalifah, R., Aloufi, M. et al. AGREEing on clinical practice guidelines for idiopathic steroid-sensitive nephrotic syndrome in children. Syst Rev 10, 144 (2021). https://doi.org/10.1186/s13643-021-01666-w).