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(A) ALP levels in serum of various animal groups. The values presented are mean ± S.E.M (n = 8). ALP *** p < 0.001 vs. sham, # p < 0.05, ## p < 0.01, ### p < 0.001 vs. OVX SHAM. (B) ACP levels in serum of various animal groups. ACP ** p < 0.01 vs. sham, # p < 0.05 ## p < 0.01 vs. OVX control. OVX SHAM—sham control, OVX—ovariectomized control, RLX—plain raloxifene hydrochloride (as standard), NRG or NRG-plain, NRG-NS.
