Table 3.
Bone parameters in various groups after formulation treatment.
| S. No. | Group | Weight (g) |
Ash Weight (g) |
Length (mm) |
Diameter (mm) |
Bone Density (g/cm3) |
Bone Inorganic Content (mg%) | |
|---|---|---|---|---|---|---|---|---|
| Ca | P | |||||||
| 1 | SHAM | 0.88 ± 0.18 | 0.07 ± 0.02 | 28.46 ± 1.28 | 2.48 ± 0.32 | 1.79 ± 0.008 | 10.27 ± 0.40 | 4.19 ± 0.08 |
| 2 | OVX Control | 0.58 ± 0.07 # | 0.03 ± 0.01 # | 27.76 ± 0.30 | 2.09 ± 0.05 | 0.54 ± 0.09 ## | 5.25 ± 0.65 ## | 3.76 ± 0.05 # |
| 3 | RLX | 0.80 ± 0.08 | 0.08 ± 0.02 | 28.01 ± 0.49 | 2.17 ± 0.01 | 1.80 ± 0.07 ** | 11.57 ± 2.19 | 4.64 ± 0.01 |
| 4 | NRG | 0.70 ± 0.07 | 0.08 ± 0.01 | 26.66 ± 1.24 | 2.54 ± 0.34 | 0.69 ± 0.07 | 11.48 ± 1.45 | 4.20 ± 0.04 |
| 5 | NRG-NS | 0.85 ± 0.12 | 0.08 ± 0.01 | 27.86 ± 1.13 | 2.56 ± 0.76 | 1.40 ± 0.29 * | 11.09 ± 0.05 | 4.06 ± 0.03 |
| 6 | Blank-NS | 0.61 ± 0.11 | 0.02 ± 0.01 | 26.43 ± 1.43 | 2.23 ± 1.52 | 0.66 ± 0.12 | 6.32 ± 0.32 | 4.12 ± 0.01 |
The values presented are mean ± S.E.M (n = 8); ** p < 0.01 and * p < 0.05 vs. OVX, # p < 0.05, ## p < 0.01, vs. sham. SHAM: sham (control), OVX: ovariectomized control, RLX: raloxifene hydrochloride, NRG: naringenin, NRG-NS: naringenin nanosuspension.