Skip to main content
. 2022 Jul 19;23(14):7974. doi: 10.3390/ijms23147974
Metabolites
5-ALA 5-aminolevulinic acid/aminolevulinate
COPRO coproporphyrin
URO uroporphyrin
PBG porphobilinogen
HMB 1-hydroxymethylbilane/pre-uroporphyrinogen
UROgen uroporphyrinogen
COPROgen coproporphyrinogen
PROTOgen protoporphyrinogen
PpIX protoporphyrin IX
Organelles
PM plasma membrane
ER endoplasmic reticulum
GA Golgi apparatus
OMM/IMM outer/inner mitochondrial membrane
IMS inner mitochondrial space
END endosome
LYSO lysosome
Enzymes
ALAS ALA-synthase
PLP pyridoxal-5’-phosphate
ALAD ALA-dehydratase
PBGD porphobilinogen deaminase
UROS uroporphyrinogen III cosynthase
UROD uroporphyrinogen decarboxylase
CPO coproporphyrinogen III oxidase
PPO protoporphyrinogen oxidase
FECH ferrochelatase
HO heme oxygenase
BVRA biliverdin reductase-A
UGT1A1 UDP-glucuronosyltransferase 1A1
Others
PDT photodynamic therapy
PDD photodynamic diagnosis
ROS reactive oxygen species
TCA tricarboxylic acid
CLIP cytosolic labile iron pool
ISC iron-sulfur cluster
CO carbon monoxide
ABCB ATP-binding cassette subfamily B member