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. 2022 Jun 21;14(7):1318. doi: 10.3390/pharmaceutics14071318

Table 3.

Blend compositions generated by I-optimal design and observed experimental data.

Input Variables
(% m/m)
Responses
MCT Oil
A
Crude Soy Lecithin
B
Tween 80
C
Salt Water
D
Droplet Size
(nm)
PDI Zeta Potential
(mV)
Temperature of Dilution
(°C)
1 12.00 2.16 11.50 74.34 40 0.093 −49 93
2 10.00 2.42 11.49 76.09 33 0.127 −73 83
3 11.16 1.50 11.38 75.95 46 0.152 −56 95
4 11.83 2.87 13.89 71.41 31 0110 −50 86
5 10.00 3.00 9.00 78.00 34 0.097 −37 85
6 10.68 1.99 14.00 73.33 33 0.128 −46 87
7 10.00 1.50 13.07 75.44 35 0.161 −48 90
8 10.00 3.00 14.00 73.00 29 0.183 −56 85
9 11.16 1.50 11.38 75.95 46 0.149 −57 95
10 12.00 1.50 9.00 77.50 72 0.065 −54 95
11 10.21 1.64 9.03 79.13 46 0.090 −35 95
12 12.00 2.16 11.50 74.34 40 0.136 −55 91
13 12.00 3.00 9.55 75.45 42 0.073 −53 89
14 11.79 1.50 12.92 73.79 43 0.101 −39 92
15 10.00 2.96 12.83 74.22 35 0.137 −56 86
16 10.97 3.00 11.45 74.58 39 0.113 −49 86
17 11.27 2.42 9.00 77.31 41 0.147 −64 87
18 10.25 1.50 10.53 77.72 40 0.089 −36 93
19 12.00 1.50 14.00 72.50 42 0.129 −41 89
20 10.67 3.00 10.10 76.22 37 0.099 −52 89
21 10.68 1.99 14.00 73.33 35 0.141 −44 87
22 10.00 2.42 11.49 76.09 33 0.177 −70 85
23 12.00 3.00 12.32 72.68 35 0.108 −52 85
24 11.27 2.42 9.00 77.31 47 0.113 −68 87