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. 2022 Jul 9;14(14):3343. doi: 10.3390/cancers14143343

Table 2.

Pretreatment quality of life and symptom burden by completion of first-line treatment in 137 newly referred patients with lung cancer, Herlev University Hospital, Denmark, 2016–17.

Completed First-Line Treatment
N Total
Mean (SD)
Yes
Mean (SD)
No
Mean (SD)
p-Value
Functioning scales (QLQ-C30)
Global QOL 135 62.1 (22.9) 68.2 (20.04) 55.2 (24.1) <0.001 *
Physical function 137 77.3 (20.0) 83.6 (15.7) 69.9 (22.1) <0.001 *
Role function 134 69.5 (27.99) 76.6 (25.7) 61.3 (27.4) 0.001 *
Emotional function 135 72.9 (22.4) 78.2 (19.1) 66.7 (24.5) 0.004 *
Cognitive function 135 87.7 (19.4) 90.9 (14.6) 83.6 (23.5) 0.035 *
Social function 134 86.9 (18.1) 92.0 (13.9) 80.9 (20.6) <0.001 *
Symptom scales and single-items (QLQ-C30 and QLQ-LC13)
Fatigue 136 34.1 (23.6) 28.3 (20.3) 41.0 (25.4) 0.002 *
Nausea/vomiting 136 7.23 (15.8) 4.7 (13.7) 10.2 (17.7) 0.049 *
Pain 135 16.7 (21.8) 12.2 (16.6) 22.1 (25.9) 0.011 *
Dyspnea 134 36.3 (30.2) 30.6 (27.6) 43.2 (31.8) 0.016 *
Insomnia 136 28.2 (31.92) 23.9 (29.5) 33.3 (34.1) 0.085
Appetite loss 136 25.98 (31.9) 20.3 (29.6) 32.8 (33.3) 0.02 *
Constipation 134 7.5 (17.6) 6.3 (14.3) 8.9 (21.1) 0.42
Diarrhea 134 7.7 (17.3) 7.3 (16.9) 8.2 (17.9) 0.77
Financial difficulties 135 5.4 (16.9) 4.5 (14.9) 6.6 (19.1) 0.49
Dyspnea (lung cancer-specific) 137 27.4 (24.6) 22.8 (22.2) 32.7 (26.9) 0.02 *
Coughing 137 43.6 (29.9) 45.5 (29.5) 41.3 (30.4) 0.41
Hemoptysis 137 6.3 (16.4) 4.9 (14.3) 7.9 (18.7) 0.30
Sore mouth 137 3.6 (11.2) 3.6 (11.8) 3.7 (10.6) 0.96
Dysphagia 136 6.4 (16.5) 5.5 (17.6) 7.4 (15.2) 0.50
Peripheral neuropathy 136 5.6 (14.9) 4.95 (11.9) 5.5 (17.6) 0.58
Alopecia 134 4.2 (17.5) 4.1 (17.4) 4.4 (17.9) 0.90
Pain in chest 134 14.9 (22.2) 10.9 (19.3) 19.7 (24.6) 0.027 *
Pain in arm or shoulder 134 12.4 (22.6) 11.7 (22.4) 13.3 (23.1) 0.68
Pain in other parts 132 18.4 (27.7) 13.9 (24.1) 24.1 (31.1) 0.042 *

* Significant at the 5% level.