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GREM1 expression is correlated with poor survival in CRC patients. (A) Representative images of GREM1 in para-carcinoma and carcinoma tissues of patients with stage IV CRC. Scale bar, 250 µm. (B) Kaplan–Meier survival analysis of 597 colon cancer patients stratified by GREM1 expression levels. Kaplan–Meier survival analysis and GREM1 mRNA expression according to FPKM value 5.31 as a cutoff value in the whole cohort. p = 0.046 by log-rank (Mantel–Cox) test.
