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The additive and synergistic inhibition of IL-8, IL-6, and MCP-1 induction in HCoV-OC43-infected MRC-5 cells after treatment with the combination of ciclesonide and dbq33b.
| Cytokine Inhibition | Synergy Score | Most Synergistic Area Score | Method |
|---|---|---|---|
| IL-8 | 11.78 ± 2.30 * | 16.28 | ZIP |
| IL-6 | 6.52 ± 1.96 | 6.84 | ZIP |
| MCP-1 | 14.93 ± 3.22 | 15.42 | ZIP |
* AVE ± S.D. of synergy scores from three independent experiments. Synergy scores were calculated and analyzed by SynergyFinder, ZIP method.
