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The synergistic inhibition of coronaviral replication in HCoV-OC43-infected MRC-5 cells and SARS-CoV-2-infected Vero E6 cells after treatment with the combination of ciclesonide and dbq33b.
| CoV Inhibition/Cell Line | Synergy Score | Most Synergistic Area Score | Method |
|---|---|---|---|
| HCoV-OC43/HCT-8 | 15.10 ± 5.40 * | 16.28 | ZIP |
| SARS-CoV-2/Vero E6 | 14.37 ± 2.76 | 18.38 | ZIP |
* AVE ± S.D. of synergy scores from three independent experiments. Synergy scores were calculated and analyzed by SynergyFinder, ZIP method.
