Figure 4.

Siderophore activities of the compounds 1–4 using C. neoformans as model organism. A) Wild‐type C. neoformans and mutant strains cfo1Δ and cft1Δ were grown on iron‐depleted medium with or without siderophore (ferroxamine) and growth was monitored two days after incubating at 30 °C. B) Mutant strains were grown in iron‐depleted medium containing 10 μM of compounds 1–4 (in the absence (Iron‐free) or presence of Fe(III) (Iron‐loaded). Growth was monitored two days after incubating at 30 °C.