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. 2022 Jul 19;2022:7896371. doi: 10.1155/2022/7896371

Figure 8.

Figure 8

Pathways enrichment results and the relative expression levels of hepatic inflammation pathway-related genes. WT: wild-type (Period2+/+) mice; KO: Per2 gene knockout (Period2−/−) mice. (a) KEGG functional analysis of the coexpressed DEGs. (b) Gene ontology (GO) functional analysis of the coexpressed DEGs. The relative expression levels of Il-1β (c), Il-6 (d), Tnf-α (e), Tlr2 (f), Tlr4 (g), Myd88 (h), and Nf-κB (i) were determined in liver tissues of Per2 knockout and wild-type mice by RT-PCR method.