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. 2022 Jul 19;2022:5509346. doi: 10.1155/2022/5509346

Figure 8.

Figure 8

The effect of HS3ST1 on SPOP/FADD/NF-κB signaling. (a) SPOP protein expression in the form of representative images, FADD, and p-p65 in A549 cells. (b) Results of expression of SPOP, FADD, and p-p65 in A549 cells. (c) The effects of SPOP overexpression or knockdown on the mRNA expression of FADD. (d) The effects of SPOP overexpression and a proteasome inhibitor MG-132 on the protein expression of FADD and p-p65 in A549 cells. (e) The quantity levels of FADD and p-p65 in A549 cells. (f) The protein levels of FADD in NSCLC tumor and adjoining normal samples. (f) The protein levels of p-p65inNSCLC tumor and adjacent normal samples. ∗∗P < 0.01 compared to control, N = 12.