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. 2022 Jul 26;13(7):650. doi: 10.1038/s41419-022-05064-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A qRT-PCR detection of miR-670-3p levels in plasma exosomes of healthy controls and patients with ESRD (n = 15). B The level of IGF-1 in the plasma of healthy people and patients with ESRD was measured by ELISA (n = 15). C Analysis of linear correlation between exosomal miR-670-3p and IGF-1 in plasma. D Analysis of coronary vascular calcification scores of normal people and patients with ESRD by multilayer spiral CT reconstruction, and representative pictures were shown (n = 15, left panel). The quantification results of CAC score in normal people and patients with ESRD (right panel). E Analysis of Spearman correlation between exosomal miR-670-3p and CAC score. F Analysis of Spearman correlation between plasma IGF-1 and CAC score. One-way ANOVA with Bonferroni’s post hoc test (A, B) and Spearman’s r test (C, E, F) were used. Data represented the mean ± SD. *p < 0.05.