Table 1.

Cytotoxicity of MA to MLA cells abrogated by 10 mM GSH

Methyl acrylate (µg/ml)	Methyl-acrylate only			Methyl acrylate + 10 mM glutathione simultaneously			Methyl acrylate treatment followed by posttreatment with 10 mM glutathione			Methyl acrylate + 10 µM 2-mercaptoethanol
	RGDT	RSG	RTG	RGDT	RSG	RTG	RGDT	RSG	RTG	RGDT	RSG	RTG
0 (Vehicle control)	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0	100.0
1.0	107.0	90.3	101.6	99.7	85.7	67.3	93.2	84.1	90.8	101.3	101.3	94.6
5.0	103.1	68.3	74.2	99.6	85.5	75.3	85.8	62.7	68.8	102.0	82.1	82.1
10.0	99.7	61.0	59.0	98.8	90.8	82.8	86.4	59.5	73.2	98.0	81.6	73.8
15.0	94.2	49.5	50.3	104.8	87.0	92.4	84.2	59.1	60.0	94.7	70.7	80.4
20.0	89.5	46.5	38.1	96.3	79.9	68.1	79.1	42.0	55.4	84.2	56.0	49.0
25.0	874	25.7	27.0	108.1	83.5	74.8	73.3	10.1	6.2	86.4	41.3	52.1
30.0	88.5	n.c	n.c	100.5	89.6	91.4	833	15.6	13.5	90.3	37.0	28.2
35.0	88.2	n.c	n.c	103.4	77 1	66.8	841	11.0	6.2	86.3	48.0	46.4

RGDT relative growth during treatment [%]; RSG relative suspension growth [%]; RTG relative total growth [%]; n.c. culture not continued due to strong cytotoxicity