Table 7.
Methyl acrylate initially added [µg/ml] | Glutathione initially added [µM] | Methyl acrylate finally recovereda [µg/ml]/%c/%d | Glutathione finally recoveredb [µmol/g cell lysate] |
---|---|---|---|
0 | 0 | ˂0.2 | 59.6 |
20 | 0 | 7.6/38 | 21.9 |
25 | 0 | 9.7/39 | 12.2 |
35 | 0 | 14.4 /41 | 10.9 |
0 | 10 | ˂0.2 | 37.3 |
20 | 10 | 6.7/33c/88d | 15.4 |
25 | 10 | 8.3/33/86 | 11.7 |
35 | 10 | 14.1/40/98 | 8.12 |
0 | 100 | ˂0.2 | 48.3 |
20 | 100 | 4.6/23/61 | 24.4 |
25 | 100 | 6.0/24/62 | 13.9 |
35 | 100 | 11.1/32/77 | 10.5 |
0 | 1000 | ˂0.2 | 49.6 |
20 | 1000 | 0.24/1.2/3.2 | 55.6 |
25 | 1000 | 0.31/1.2/3.2 | 52.8 |
35 | 1000 | 0.47/1.3/3.3 | 60.4 |
aIn the end of the mutagenicity experiment recovered in the culture supernatant (in the culture cell lysate ˂1 µg/ml)
bIn the end of the mutagenicity experiment recovered in the culture cell lysate (in the culture supernatant below detection)
cCompared with the initially added amount
dCompared with the residual amount after the exposure period in absence of GSH