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. 2022 Jun 15;96(9):2573–2587. doi: 10.1007/s00204-022-03322-1

Table 7.

Methyl acrylate and glutathione recoveries in the end of the mutagenicity experiments

Methyl acrylate initially added [µg/ml] Glutathione initially added [µM] Methyl acrylate finally recovereda [µg/ml]/%c/%d Glutathione finally recoveredb [µmol/g cell lysate]
0 0 ˂0.2 59.6
20 0 7.6/38 21.9
25 0 9.7/39 12.2
35 0 14.4 /41 10.9
0 10 ˂0.2 37.3
20 10 6.7/33c/88d 15.4
25 10 8.3/33/86 11.7
35 10 14.1/40/98 8.12
0 100 ˂0.2 48.3
20 100 4.6/23/61 24.4
25 100 6.0/24/62 13.9
35 100 11.1/32/77 10.5
0 1000 ˂0.2 49.6
20 1000 0.24/1.2/3.2 55.6
25 1000 0.31/1.2/3.2 52.8
35 1000 0.47/1.3/3.3 60.4

aIn the end of the mutagenicity experiment recovered in the culture supernatant (in the culture cell lysate ˂1 µg/ml)

bIn the end of the mutagenicity experiment recovered in the culture cell lysate (in the culture supernatant below detection)

cCompared with the initially added amount

dCompared with the residual amount after the exposure period in absence of GSH