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. 2022 Jun 15;96(9):2573–2587. doi: 10.1007/s00204-022-03322-1

Table 8.

Ethyl acrylate and glutathione recoveries in the end of the mutagenicity experiments

Ethyl acrylate initially added [µg/ml] Glutathione initially added [µM] Ethyl acrylate finally recovereda [µg/ml]/%c/%d Glutathione finally recoveredb [µmol/g cell lysate]
0 0 ˂0.2 53.3
20 0 11/55 9.28
25 0 13/52 8.39
35 0 18/51 5.55
0 10 ˂0.2 56.25
20 10 7.5/37c/68d 16.51
25 10 me 10.98
35 10 13/37/72 6.22
0 100 ˂0.2 65.02
20 100 5.3/26/48 22.83
25 100 6.4/26/49 17.30
35 100 8.9/25/49 14.48
0 1000 ˂0.2 48.08
20 1000 0.27/1.3/2.5 84.74
25 1000 0.48/1.9/3.7 82.12
35 1000 0.73/2.1/4.1 82.70

aIn the end of the mutagenicity experiment recovered in the culture supernatant (in the culture cell lysate ˂1 µg/ml)

bIn the end of the mutagenicity experiment recovered in the culture cell lysate (in the culture supernatant 0, except after the initial addition of 1000 µM GSH 4.15, 2.05, 2.97 and 3.05 µmol/g cell lysate after co-incubation with 0, 20, 25 and 35 µg ethyl acrylate/ml, respectively

cCompared with the initially added amount

dCompared with the residual amount after the exposure period in absence of GSH

eMistake