Table 7.

Food consumption, feces and urine production during the 24 h prior to sacrifice, in control mice and in animals treated orally with different doses of CTX3C, gambierone, MTX3 and MTX1 during 28 days

Control (n = 7)
Food consumption (g)	5.3 ± 0.7
Feces (g)	1.7 ± 0.3
Urine (ml)	2.9 ± 0.9
CTX3C (n = 3)	10 ng/kg	32 ng/kg	100 ng/kg
Food consumption (g)	3.9 ± 0.6	5 ± 0.9	4.7 ± 0.2
Feces (g)	1.6 ± 0.2	1.4 ± 0.4	1.3 ± 0.1
Urine (ml)	1.8 ± 0.4	1 ± 0.02	1.1 ± 0.5
Gambierone (n = 3)	172 ng/kg	500 ng/kg	1760 ng/kg
Food consumption (g)	2.9 ± 1.2	5.4 ± 0.6	5.2 ± 0.3
Feces (g)	1 ± 0.5	1.4 ± 0.4	1.6 ± 0.2
Urine (ml)	4.5 ± 1.6	1.3 ± 0.7	1.3 ± 0.2
MTX3	500 ng/kg (n = 2)	1760 ng/kg (n = 3)
Food consumption (g)	3.8 ± 0.4	3.5 ± 0.3
Feces (g)	1.2 ± 0.4	0.8 ± 1.4
Urine (ml)	0.5 ± 0.3	2.2 ± 1.5
MTX1	800 ng/kg (n = 3)	2560 ng/kg (n = 3; 1 surviving mouse)	5000 (n = 5), no surviving animals
Food consumption (g)	5.8 ± 0.8	5.2
Feces (g)	1.5 ± 0.1	1.5
Urine (ml)	1 ± 0.3	0.2

Values are expressed as mean ± SEM