Table 1.
Summary of changes in the 3 animal models of MS.
| POVPC | LPC | EAE | |
|---|---|---|---|
| CD68 | Upregulated | Upregulated | Upregulated |
| OLIG2 | Upregulated | Upregulated | No change |
| GFAP | Downregulated | Downregulated | No change |
| SOD1 | Upregulated | Upregulated | Upregulated |
| CD68+ SOD1+ | Upregulated | Upregulated | Upregulated |
| GFAP+ SOD1+ | No change | Upregulated | Downregulated |
| HO-1 | Upregulated | Upregulated | No change |
| CD68+ HO-1+ | Upregulated | No change | Upregulated |
| GFAP+ HO-1+ | No change | No change | No change |
| PRDX5 | Upregulated | Upregulated | Upregulated |
| CD68+ PRDX5+ | Upregulated | Upregulated | Upregulated |
| GFAP+ PRDX5+ | No change | Upregulated | Upregulated |
| GPX4 | Upregulated | Upregulated | Upregulated |
| CD68+ GPX4+ | Upregulated | Upregulated | Upregulated |
| OLIG2+ GPX4+ | Downregulated | Downregulated | Upregulated |
This table lists the changes in the level of CD68, OLIG2, and GFAP positive cells, and their expression of particular antioxidant enzymes in the three animal models of MS.