Table 1.
Characteristics of participants with normoglycemia and prediabetes
| Characteristics | Normoglycemia (N=20) | Prediabetes (N=20) | P-value |
|---|---|---|---|
| Demographic and anthropometric parameters | |||
| Age (years) | 51.8±6.6 | 50.9±5.6 | 0.625 |
| Male, N (%) | 13 (65.0) | 13 (65.0) | >0.999 |
| History of smoking, N (%) | 10 (50.0) | 7 (35.0) | 0.337 |
| History of alcohol drinking, N (%) | 16 (80.0) | 12 (60.0) | 0.168 |
| Underlying diseases, N (%) | |||
| Hypertension | 4 (20.0) | 3 (15.0) | 0.677 |
| Dyslipidemia | 9 (45.0) | 7 (35.0) | 0.519 |
| NAFLD | 0 (0.0) | 1 (5.0) | 0.311 |
| Body weight (kg) | 62.7±12.8 | 63.7±12.4 | 0.814 |
| Body mass index (kg/m2) | 23.1±4.6 | 24.1±4.0 | 0.501 |
| SBP (mmHg) | 130.5±15.5 | 129.5±14.5 | 0.842 |
| DBP (mmHg) | 81.3±8.1 | 82.1±10.6 | 0.790 |
| Waist circumference (cm) | 84.8±10.8 | 85.4±10.7 | 0.878 |
| Waist hip circumference ratio | 0.91±0.07 | 0.91±0.06 | 0.825 |
| HIV-related parameters | |||
| Duration of HIV infection (years) | 15.2±6.1 | 14.4±5.4 | 0.682 |
| Type of ART regimen, N (%) | |||
| NNRTI-based | 13 (65.0) | 13 (65.0) | >0.999 |
| PI-based | 7 (35.0) | 7 (35.0) | >0.999 |
| Duration of ART (years) | 11.5±6.1 | 11.9±5.1 | 0.834 |
| CD4 cell counts (cells/mm3) | 559.8±264.0 | 475.0±204.5 | 0.263 |
| Biochemical parameters | |||
| FPG (mg/dL) | 91.8 ±7.9 | 101.4±13.6 | 0.009 |
| 2h PG (mg/dL) | 113.5±37.0 | 138.7±37.3 | 0.041 |
| HbA1c (%) | 5.32±0.21 | 5.99±0.22 | <0.001 |
| Triglycerides (mg/dL) | 130.5 (81.8 – 185.3) | 134.0 (99.5 – 198.5) | 0.379 |
| HDL cholesterol (mg/dL) | 51.2±11.6 | 46.2±11.4 | 0.181 |
| LDL cholesterol (mg/dL) | 141.3±36.0 | 130.0±33.4 | 0.308 |
| Total cholesterol (mg/dL) | 219.0±42.0 | 203.4±36.3 | 0.215 |
Data were presented as mean±SD or median (interquartile range).
2h PG = 2-h plasma glucose; ART = antiretroviral therapy; DBP = diastolic blood pressure; FPG = fasting plasma glucose; HbA1c = hemoglobin A1c; HDL = high-density lipoprotein; LDL= low-density lipoprotein; NAFLD = non-alcoholic fatty liver disease; NNRTI = non-nucleoside reverse transcriptase inhibitor; PI = protease inhibitor; SBP = systolic blood pressure