TABLE 1.

Insulin resistance, diabetes and obesity.

Non-coding RNA	Non-coding RNA function	Pathology	Resveratrol effect	Final effect	References
mmu-miR-363-3p		Insulin resistance	↑miRNA	Insulin resistance Improvement via the PI3K-Akt pathway in HepG2 cells	Shu et al., (2020)
miR-33 miR-122	miRNAs associated with the risk for developing T2D	Insulin resistance	↓ miRNAs	Insulin resistance improvement in hepatic cells	Baselga-Escudero et al., (2013)
miR-18a-5p	Controls autophagy activity through ATM.	Diabetic nephropathy	↑miRNA	Diabetic nephropathy amelioration by increasing autophagy in mouse kidney tissues and podocytes cell line	Xu et al., (2017)
miR-155		Obesity	↑miRNA	Downregulation of the adipogenic transcription factor CEBP-β in 3T3-L1 preadipocytes	Eseberri et al., (2017)
miR-539-5p		Obesity	↑miRNA	Inhibition of de-novo lipogenesis in white adipose tissue	Gracia et al., (2016)

The function of miRNAs, in the column “miRNA, function” is referred to the specific pathology reported in the table.

ATM, Atactic telangiectasis mutation; CEBP-β, CCAAT enhancer-binding protein β; ↑, increased expression/activity; ↓, decreased expression/activity.