TABLE 2.
Inflammation.
| Non-coding RNA | Non-coding RNA function | Pathology | Resveratrol effect | Final effect | References |
|---|---|---|---|---|---|
| MALAT-1 (lncRNA) | Pro-inflammatory | Sepsis-induced inflammation | ↓ lncRNA | Sepsis-induced AKI relief by suppressing the MALAT1/MiR-205 axis in rats | Wang et al., (2021) |
| miR-Let7A | Anti-inflammatory | Inflammation | ↑miRNA | Anti-inflammatory response in THP-1 macrophage | Song et al., (2016) |
| miR-34a | Potentially inhibits the T-regulatory cells mediated immune response by targeting FOXP3 | Allergic asthma and associated inflammation in the lungs | ↓ miRNA | Attenuation of allergy/asthma symptoms via FOXP3 over expression in mice | Alharris et al., (2018) |
| miR193-a | Anti-inflammatory action | SEB-induced acute lung injury | ↓ miRNA | Protection against SEB-mediated toxicity by triggering anti-inflammatory pathways in mice | Alghetaa et al., (2018) |
| miRNA-101b miRNA-455 | Anti-inflammatory properties | Colitis-associated tumorigenesis | ↑miRNAs | Mitigation of colitis-associated tumorigenesis in mice | Altamemi et al., (2014) |
The function of miRNAs, in the column “miRNA, function” is referred to the specific pathology reported in the table.
AKI, acute kidney injury; SEB, Staphylococcal enterotoxin B; FOXP3, forkhead box P3; ↑, increased expression/activity; ↓, decreased expression/activity.