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. 2022 Jul 13;13:953761. doi: 10.3389/fimmu.2022.953761

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Copyright © 2022 Ou, Luo, Wei, Qin, Du, Wang and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subgroup analyses and safety results in lung cancer. (A) PD-(L)1 inhibitors monotherapy versus chemotherapy in non-small cell lung cancer; (B) PD-(L)1 inhibitors plus chemotherapy versus chemotherapy in non-small cell lung cancer; (C) PD-(L)1 inhibitors plus chemotherapy versus chemotherapy in small cell lung cancer. CT, chemotherapy; n, the number of included systematic reviews; EFGR, epidermal growth factor receptor; KRAS, kirsten rat sarcoma viral oncogene; ECOG, Eastern Cooperative Oncology Group; PS, performance status; AEs, adverse events; irAEs, immune-related adverse events; High-grade, ≥3 grade.