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Cytotoxicity in Caco-2 (A) or HT29-MTX-E12 (B) monocultures after treatment with basolateral supernatants ( = 48h; relative concentration 0.25, 0.5 or 1) from stable (full bars) or inflamed (open bars) triple cultures (WT, CASP1-/- or NLRP3-/- THP-1 cells) for 48 (h) Cytotoxicity was assessed via LDH assay. Mean ± SD of N = 5, *p < 0.05 compared to the untreated control.
