Table 1.

Recommendation on Cancer-free Wait Time

Cancer Type	Classification	Recommended Wait*	Comments
Breast
	DCIS/stage 1	No wait
	Stage 2	1-2 years
	Stage 3	3-5 years
Colorectal
	Stage 1 (T1 or T2,N0,M0)	1-2 years
	Stage 2 (T3,N0,M0)	2 years
	Stage 2 (T4,N0,M0)	3-5 years	5 years for high-risk features
	Stage 3 (N+)	5 years
Anal
	Invasive, HPV-related	5 years
Prostate
	PSA < 10, Gleason < 6,T1-T2a	No wait	If nomogram CS death over 15 yrs < 10%
	PSA > 10, Gleason 7 (Grade 2,3) T2b	No wait
	PSA > 20 ng/mL, high volume Gleason 7	No wait	Treatment suggested
	Gleason 8-10, T3
Renal cell
	T1a (<4 cm) N0, M0	No wait
	T1b (>4 cm ≤ 7 cm) N0, M0, Fuhrman grade G1-2	No wait
	T1b (>4 cm ≤ 7 cm) N0, M0, Fuhrman grade G3-4	1-2 years
	T3 or T4 tumors	2 years minimum
Bladder
	Low risk NMIBC	6 months	If no recurrence at 6 months
	Intermediate risk NMIBC	6 months	If no recurrence at 6 months
	High risk NMIBC	2 years	After therapy
	Muscle invasive	2 years	After radical cystectomy
Gynecologic
	Stage 1A, 1B, grade 1-2 endometrial cancer without lymph-vascular space invasion	No wait
	Stage 1A. 1B, 1C grade 1-2 epithelial ovarian cancer
	Stage 1A1, 1A2 squamous/adenocarcinoma of the cervix
	Stage 1 and 2 endometrial cancer with risk factors and Stage 1b cervical cancer	2-3 years
	Serous, clear cell or carcinosarcoma of the uterus (all stages)	5 years
	Stage 3 grade 1-3 endometrial cancer of the uterus
	Stage 2,3 epithelial ovarian cancer
	Stage 2,3 squamous cell/adenocarcinoma cervical cancer
Non-small cell lung
	Early-stage disease (<1b)	3-5 years
	Stage 1b-3a	5 years
Melanoma
	In situ	No wait time
	Stages ≤ 2a	1 year
	Stage 3a	1-2 years
	Stage 2b, 2c, 3b	2-4 years
Lymphoma
		2 years after remission

Abbreviations: CS death, cancer-specific death; DCIS, ductal carcinoma in situ; NMIBC, non–muscle-invasive bladder cancer.

^*Wait times begin after therapy, if therapy is warranted.