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. 2022 Jul 13;13:914167. doi: 10.3389/fimmu.2022.914167

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Copyright © 2022 Torresi, Edeling, Nolan and Godfrey

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mutations in the viral spike identified in Alpha, Beta, Delta, Gamma, Mu and Omicron BA.1 SARS-CoV-2 variants showing the significant clusters of changes in both the N-terminal domain (NTD) and RBD. FP, fusion peptide; HR1, heptad repeat 1; CH, central helix; CD, connector domain; HR2, heptad repeat 2; TMD, transmembrane domains.