Table 5.
Analysis of factors affecting the prognosis of sepsis patients.
| Survivors (N=75) | Non-survivors (N=49) | χ2/U | P | |
|---|---|---|---|---|
| Age | 56.00 (51.00,62.00) | 66.00 (51.00,75.00) | 1300.000 | 0.006 |
| Female | 19 (33.93%) | 24 (48.98%) | 7.316 | 0.007 |
| Fever | 52 (69.33%) | 38 (77.56%) | 1.006 | 0.316 |
| Heart rate | 101.00 (85.00,118.00) | 102.00 (90.00,120.00) | 1561.500 | 0.158 |
| Medical history | ||||
| immune-related diseases | 14 (18.67%) | 16 (32.65%) | 3.161 | 0.075 |
| Coronary heart disease | 11 (14.67%) | 6 (12.25%) | 0.147 | 0.701 |
| Hypertension | 30 (40.00%) | 18 (36.74%) | 0.133 | 0.715 |
| Diabetes | 13 (17.33%) | 11 (22.45%) | 0.497 | 0.481 |
| Hemodialysis | 15 (20.00%) | 9(18.37%) | 0.051 | 0.822 |
| Surgery | 32 (42.67%) | 28 (57.14%) | 2.487 | 0.115 |
| Disease and severity assessment scores | ||||
| Admission APACHE II score | 18 (13,21) | 18 (17,21) | 1551.000 | 0.141 |
| Biochemical indicators | ||||
| WBC | 11.14 (8.355,14.465) | 10.26 (3.64,17) | 1709.000 | 0.511 |
| Procalcitonin | 1.19 (0.39,11.35) | 3.6(0.57,10.00) | 1747.000 | 0.644 |
| C-reactive protein | 73.20 (10.80,145.09) | 88.47 (28.00,162.45) | 1622.000 | 0.271 |
| Platelets | 179.00 (123.5.00,247.50) | 114.00 (30.00,193.00) | 1204.000 | 0.001 |
| Neutrophil% | 87.00 (78.85,90.85) | 84.20 (64.80,92.30) | 1552.500 | 0.145 |
| Aspartate | 29.00 (16.50,56.50) | 23.00 (17.00,47.00) | 1642.500 | 0.319 |
| Bilirubin | 11.90 (6.95,19.55) | 13.92 (10.00,21.30) | 1611.000 | 0.247 |
| Creatinine | 80.00 (55.00,124.50) | 85.00 (57.10,156.00) | 1588.500 | 0.203 |
| Myoglobin | 70.75 (37.29,251.15) | 700.00 (350.50,1052.00) | 410.500 | <0.001 |
| Cholinesterase | 4.20 (3.00,6.45) | 3.90 (2.50,6.00) | 1651.000 | 0.340 |
| Brain natriuretic peptide | 549.00 (161.30,3636.00) | 1063.00 (411.00,3713.00) | 1511.500 | 0.096 |
| Prothrombin time | 12.60 (11.40,14.70) | 12.70 (11.20,15.30) | 1781.000 | 0.773 |
| Fibrinogen | 3.70 (2.82,5.02) | 3.45 (2.52,4.42) | 1650.000 | 0.338 |
| ICU treatment | ||||
| Use of vasoactive drugs | 63 (84.00%) | 42 (85.71%) | 0.067 | 0.796 |
| Hemodialysis | 15 (20.00%) | 9(18.37%) | 0.051 | 0.822 |
| Tracheotomy | 63 (81.33%) | 42 (85.71%) | 0.404 | 0.525 |
| Virus positive (mNGS) | 6 (8.00%) | 8(16.3%) | 2.052 | 0.152 |
| Sequence number | ||||
| Negative | 24 (32.00%) | 16 (32.65%) | 6.817 | 0.227 |
| 0–50 | 27 (36.00%) | 9 (18.37%) | ||
| 51–100 | 6 (8.00%) | 4 (8.16%) | ||
| 100–500 | 9 (12.00%) | 9 (18.37%) | ||
| 500–1000 | 3 (4.00%) | 2 (4.08%) | ||
| >1000 | 6 (8.00%) | 9 (18.37%) | ||
| Pathogen detection (mNGS) | ||||
| Negative | 24 (32.00%) | 16 (32.65%) | 3.284 | 0.194 |
| Infection with a single pathogen | 45 (60.00%) | 24 (48.98%) | ||
| Mixed infection | 6 (8.00%) | 9 (18.37%) | ||
| Blood culture positive | 15 (20.00%) | 9 (18.37%) | 0.051 | 1.000 |