Table 1.
Genes related to courtship LTM in Drosophila.
| Gene | Function | Related brain neurons | References |
|---|---|---|---|
| CrebB | Transcription factor | – | Sakai et al., 2004 |
| MBs (α/β & γ lobes) | Inami et al., 2020 | ||
| period | Circadian clock gene | Clock neurons | Sakai et al., 2004 |
| Clock neurons | Donlea et al., 2009 | ||
| LNds | Suzuki et al., 2022 | ||
| Notch | Transcription factor | MBs | Presente et al., 2004 |
| Orb2 | Drosophila homolog for CPEB | MBs | Keleman et al., 2007 |
| MBs (γ lobes) | Kruttner et al., 2015 | ||
| blistered | Drosophila homolog for serum response factor (SRF) | Clock neurons | Donlea et al., 2009 |
| Dominant temperature sensitive 3 | Ecdysone synthetic pathway | – | Ishimoto et al., 2009 |
| Ecdysone receptor | Ecdysone receptor | MBs | Ishimoto et al., 2009 |
| Histone deacetylase 1 | Histone deacetylase | MBs | Fitzsimons and Scott, 2011 |
| small conductance calcium-activated potassium channel | Potassium channel | PNs | Abou Tayoun et al., 2012 |
| painless | TRP channnel | MBs & IPCs | Sakai et al., 2012 |
| Histone deacetylase 4 | Histone deacetylase | MBs | Fitzsimons et al., 2013 |
| Pigment-dispersing factor | Neuropeptide | l-LNvs | Inami et al., 2020 |
| Pdf receptor | Neuropeptide receptor | – | Inami et al., 2020 |
| apterous | Transcription factor | MBs (α/β lobes) & l-LNvs | Inami et al., 2021 |
| Chip | Cofactor of Apterous | MBs (α/β lobes) | Inami et al., 2021 |
| Resistant to dieldrin | GABAA receptor | l-LNvs | Inami et al., 2021 |
| Ecdysis triggering hormone | Master hormone in ecdysis | – | Lee and Adams, 2021 |
| ETHR | Ecdysis triggering hormone receptor | MBs (γ lobes) | Lee and Adams, 2021 |
MBs, mushroom bodies; LNds, dorsal lateral clock neurons; l-LNvs, large ventral lateral clock neurons; PNs, olfactory projection neurons; IPCs, insulin-producing cells.