Table 1.
Clinical and Laboratory Characteristics in Patients With GBS and Healthy Controls .
| Controls | Patients with GBS | |||
|---|---|---|---|---|
| Characteristics | N=153 | N=147 | t/z/x2 | P value |
| Demographic | ||||
| Age,y | 47.0 (31.5-60.0) | 48.0 (33.0-60.0) | -0.535 | 0.592 |
| Sex,male | 85 (55.6) | 82 (55.8) | 0.002 | 0.968 |
| Medical history, n (%) | ||||
| Hypertension | 36 (23.5) | 39 (26.5) | 0.360 | 0.548 |
| Diabetes mellitus | 25 (16.3) | 19 (12.9) | 0.698 | 0.403 |
| Heart disease | 12 (7.8) | 9 (6.1) | 0.341 | 0.559 |
| Cigarette smoking | 25 (16.3) | 41 (27.9) | 6.487 | 0.011 |
| Alcohol consumption | 16 (10.5) | 36 (24.5) | 10.302 | 0.001 |
| Surgery | 10 (6.5) | 36 (24.5) | 18.615 | < 0.001 |
| Trauma | 1 (0.7) | 19 (12.9) | 18.114 | < 0.001 |
| Hyperlipidemia | 15 (9.8) | 11 (7.5) | 0.510 | 0.475 |
| Preceding infection | 28 (18.3) | 91 (61.9) | 59.561 | < 0.001 |
| Clinical features | ||||
| SBP, mmHg | 119.86 ± 15.19 | 133.44 ± 17.32 | -9.858 | < 0.001 |
| DBP, mmHg | 72.42 ± 9.72 | 84.22 ± 11.00 | -7.226 | < 0.001 |
| BMI, kg/m2 | 23.50 (20.85-25.60) | 24.22 (21.48-26.45) | -2.104 | 0.035 |
| Laboratory results | ||||
| Triglyceride, mmol/L | 0.88 (0.63-1.21) | 1.24 (0.88-1.93) | -6.838 | < 0.001 |
| Total cholesterol, mmol/L | 4.41 ± 0.69 | 4.20 ± 0.87 | 2.315 | 0.021 |
| HDL cholesterol, mmol/L | 1.56 (1.37-1.78) | 1.09 (0.93-1.25) | -11.175 | < 0.001 |
| LDL cholesterol, mmol/L | 2.48 ± 0.66 | 2.55 ± 0.78 | -0.831 | 0.406 |
| Remnant cholesterol, mmol/L | 0.36 (0.29-0.43) | 0.49 (0.37-0.62) | -6.949 | < 0.001 |
| ApoA1, g/L | 1.49 (1.35-1.63) | 1.14 (1.02-1.28) | -10.902 | < 0.001 |
| ApoB, g/L | 0.74 ± 0.17 | 0.89 ± 0.21 | -6.779 | < 0.001 |
| Homocysteine, μmol/L | 7.60 (6.79-8.41) | 11.01 (8.70-12.69) | -10.450 | < 0.001 |
| Dyslipidemia index, n (%) | 95.223 | < 0.001 | ||
| 0 | 110 (71.9) | 27 (18.4) | ||
| 1 | 20 (13.1) | 44 (29.9) | ||
| 2 | 22 (14.4) | 45 (30.6) | ||
| ≥3 | 1 (0.6) | 31 (21.1) | ||
Data presented as mean ± SD, median (Q1-Q3) or percentage. DBP, diastolic blood pressure; SBP, systolic blood pressure; BMI, Body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; GBS, Guillain-Barré syndrome; APOA1, apolipoprotein A1; APOB, apolipoprotein B.