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. 2022 Jul 13;13:946825. doi: 10.3389/fimmu.2022.946825

Table 3.

Characteristics of Patients with GBS According to Remnant Cholesterol Quartile.

Remnant cholesterol, mmol/L P Trend
Characteristics All patients Q1 (<0.37) Q2 (0.37-0.49) Q3 (0.49-0.62) Q4 (>0.62)
Patients 147 33 40 35 39
Age, years 48.0 (33.0-60.0) 39.0 (25.0-60.0) 43.5 (29.3-61.0) 52.0 (36.0-60.0) 52.0 (44.0-60.0) 0.033
Sex, male 82 (55.8) 18 (54.5) 22 (55) 16 (45.7) 26 (66.7) 0.676
WBC count, 109/L 6.38 ± 2.20 7.07 ± 2.29 8.25 ± 3.36 7.82 ± 2.36 7.82 ± 2.36 0.003
Lymphocyte count, 109/L 1.69 ± 0.64 1.74 ± 0.59 1.96 ± 0.87 2.06 ± 1.08 2.06 ± 1.08 0.141
Monocyte count, 109/L 0.40 ± 0.15 0.49 ± 0.19 0.54 ± 0.27 0.50 ± 0.22 0.50 ± 0.22 0.029
GBS disability score at entry 0.002
0 or 1 9 (6.1) 1 (3.0) 6 (15.0) 1 (2.9) 1 (2.6)
2 47 (32.0) 20 (60.6) 17 (42.5) 3 (8.6) 7 (17.9)
3 45 (30.6) 4 (12.1) 7 (17.5) 14 (40.0) 20 (51.3)
4 40 (27.2) 6 (18.2) 9 (22.5) 17 (48.5) 8 (20.5)
5 6 (4.1) 2 (6.0) 1 (2.5) 0 (0) 3 (7.7)
GBS disability score at discharge < 0.001
0 or 1 55 (37.4) 18 (54.5) 23 (57.5) 5 (14.3) 9 (23.1)
2 40 (27.2) 8 (24.3) 10 (25.0) 10 (28.6) 12 (30.8)
3 30 (20.4) 4 (12.1) 4 (10.0) 11 (31.4) 11 (28.2)
4 18 (12.3) 2 (6.1) 2 (5.0) 9 (25.7) 5 (12.8)
5 4 (2.7) 1 (3.0) 1 (2.5) 0 (0) 2 (5.1)
Disease remission score 0.079
0 53 (36.1) 8 (24.2) 11 (27.5) 17 (48.6) 17 (43.6)
1 75 (51.0) 21 (63.6) 22 (55.0) 13 (37.1) 19 (48.7)
2 18 (12.2) 4 (12.1) 7 (17.5) 5 (14.3) 2 (5.1)
3 1 (0.7) 0 (0) 0 (0) 0 (0) 1 (2.6)
MRC sum score 44.90 ± 15.09 48.67 ± 11.55 46.95 ± 15.71 43.51 ± 13.42 40.85 ± 17.69 0.022
24-h intrathecal IgG 3.18 (-0.21-19.29) 2.24 (0.27-22.58) 6.75 (0.31-24.05) 3.94 (-9.08-17.24) 2.62 (-7.77-8.98) 0.188
CSF-ALB, mg/dl 0.37 (0.24-0.71) 0.35 (0.24-0.63) 0.39 (0.20-0.71) 0.43 (0.22-0.78) 0.33 (0.26-0.81) 0.448
Serum-ALB, mg/dl 38.37 ± 6.74 39.66 ± 6.18 39.93 ± 8.45 36.06 ± 4.68 37.37 ± 5.94 0.017
CSF-IgG, mg/ml 0.063 (0.036-0.183) 0.058 (0.035-0.149) 0.575 (0.28-0.160) 0.096 (0.039-0.25) 0.062 (0.038-0.215) 0.292
Serum-IgG, mg/ml 12.95 (10.40-24.53) 12.80 (11.30-19.80) 11.4 (10.23-16.70) 19.95 (11.70-31.20) 13.90 (9.88-25.85) 0.308
CSF-Pro, mg/dl 59.25 (38.80-110.64) 53.90 (38.35-89.55) 57.48 (31.45-110.81) 72.38 (36.24-134.07) 53.3 (39.34-133.52) 0.215
CSF-WBC,/ul 4.0 (2.0-7.5) 5.0 (2.0-9.0) 3.5 (2.0-6.75) 4.5 (2.0-5.25) 3.0 (2.0-7.5) 0.223
Albuminocytologic dissociation 0.522
Yes 62 (42.2) 15 (48.4) 14 (35) 13 (28.9) 20
No 85 (57.8) 18 (52.6) 26 (65) 22 (71.1) 19

WBC, white blood cell; CSF, cerebrospinal fluid; ALB, albumin; 24-h intrathecal IgG, intrathecal Immunoglobulin G synthesis rate of 24 hours;Pro, total protein.