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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: J Natl Compr Canc Netw. 2022 Jul;20(7):783–791.e1. doi: 10.6004/jnccn.2022.7008

Table 1.

Baseline characteristics and treatment details, unmatched and matched cohort.

Unmatched cohort Matched cohort
Overall No radiotherapy Radiotherapy P-value Overall No radiotherapy Radiotherapy P-value
n = 424 n = 229 n = 195 n = 300 n = 150 n = 150
Female, n (%) 189 (44.6) 92 (40.2) 97 (49.7) 0.06 147 (49.0) 72 (48.0) 75 (50.0) 0.82
Age, years (median [IQR]) 64 [57, 70] 64 [58, 69] 64 [57, 70] 0.85 64 [57, 70] 65 [58, 70] 64 [57, 70] 0.57
Performance status, n (%) <0.001* 0.91
 WHO 0 222 (52.4) 139 (60.7) 83 (42.6) 150 (50.0) 76 (50.7) 74 (49.3)
 WHO 1 202 (47.6) 90 (39.3) 112 (57.4) 150 (50.0) 74 (49.3) 76 (50.7)
BMI, kg/m2 (median [IQR]) 26 [23, 29] 26 [23, 30] 26 [24, 29] 0.78 26 [24, 30] 26 [23, 30] 26 [24, 29] 0.77
Tumor location: Head/uncinate, n (%) 335 (79.0) 184 (80.3) 151 (77.4) 0.54 229 (76.3) 117 (78.0) 112 (74.7) 0.59
Tumor size on CT, mm (median [IQR]) 34 [26, 41] 33 [26, 41] 34 [27, 43] 0.29 34 [27, 41] 34 [26, 41] 34 [27, 41] 0.58
Pre-treatment CA 19–9, U/mL (median [IQR]) 196 [48, 653] 178 [42, 578] 232 [75, 706] 0.13 198 [46, 653] 157 [30, 582] 238 [73, 710] 0.14
Number of cycles, n (%) 0.001* 0.88
 1–4 cycles 142 (33.5) 95 (41.5) 47 (24.1) 92 (30.7) 48 (32.0) 44 (29.3)
 5–8 cycles 230 (54.2) 109 (47.6) 121 (62.1) 172 (57.3) 84 (56.0) 88 (58.7)
 >8 cycles 52 (12.3) 25 (10.9) 27 (13.8) 36 (12.0) 18 (12.0) 18 (12.0)
* =

significant p-value <0.05.

Abbreviations: BMI, body mass index; CA 19-9, carbohydrate antigen 19-9; CT, computed tomography; IQR, interquartile range; n, number; WHO, World Health Organization. Missing data: BMI (n=6), tumor size (n=12), CA 19-9 (n=31).