Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Txnl4a knockdown affects neural crest formation. (A) Increasing amounts of Txnl4MO, 10 ng (+), 100 ng (++) and 500 ng (+++), block translation directed by txnl4a mRNA. (-) Translation without Txnl4MO. (B) Phenotype of Txnl4MO-injected embryos (30 ng) on neural crest (yellow arrows) and placode (red arrows) gene expression at stage 15. The gene analyzed in each panel is indicated in the lower left corner. D indicates dorsal view, anterior to top. L-cs indicates lateral view control side, anterior to left. L-is indicates lateral view injected side, anterior to right. (C) Quantification of the phenotypes. The numbers in each bar indicate the number of embryos analyzed. (D) sox10 expression in Txnl4MO-injected embryos is partially restored by expression of Xenopus Txnl4 resistant to the MO. The injected side is indicated by an asterisk. Dorsal views, anterior to top. (E) Quantification of the results. The numbers in each bar indicate the number of embryos analyzed. Statistically significant differences are indicated (*) p-value < 0.05 (Chi-squared test).