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Effects of indoxyl sulfate (IS, μM) and MK571 (μM) on the accumulation of glutathione S-methylfluorescein (GSMF), a fluorescent substrate of MRP 2 in MDCKII-MRP 2 cells (**P < 0.01), indicating that IS did not affect the MRP 2-mediated efflux transport of GSMF.