Table 3.

The linearity, LLOQ, and R² of wogonoside, apigenin-7-O-glucuronide and baicalin in the bile and blood. The accuracies (%) at each concentrations of the standard curves were presented.

Analytes	Linearity		LLOQ (nM)		R2
	Bile	Blood	Bile	Blood	Bile	Blood
Wogonoside	10.0–5000.0	1.56–4000.0	10.0	1.56	0.983	0.991
Apigenin-7-O-glucuronide	10.0–5000.0	1.56–4000.0	10.0	1.56	0.996	0.989
Baicalin	10.0–5000.0	1.56–4000.0	10.0	1.56	0.995	0.992

Conc.(nM)	Accuracy in Blood (%)			Conc.(nM)	Accuracy in Bile (%)
	Wogonoside	Apigenin-O-7-glucuronide	Baicalin		Wogonoside	Apigenin-O-7-glucuronide	Baicalin
1.56	92.7	98.2	112	10	90.8	86.9	97.9
3.12	111	135	81.1	20	110	119	86.7
6.25	112	118	90.7	39	109	108	124
12.5	86.1	93	102	78	111	98.9	100
25	112	111	94.3	156	113	91	103
50	88.1	77.2	109	312	108	118	115
100	98.7	91.4	102	625	96.7	108	100
200	101	100	110	1250	98.1	107	96.9
400	98	85.1	100	2500	85.2	95.5	86.8
				5000	79.5	80.9	86.6