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. 2022 Jul 15;39(3):433–438. doi: 10.5114/ada.2022.117543

Table 1.

Mechanism of action of resveratrol against asthma

Induce Inhibit

  • CD4+CD25+FOXP3

  • Interleukin 10

  • Myeloid differentiation primary response 88

  • Hydroxyproline

  • Immunoglobulin E

  • Immunoglobulin G2A

  • TNF-α

  • TGF-β

  • TGF-β1 calpain

  • CINC-1

  • Prostaglandin E2

  • GM-CSF

  • Fosfodiesterase-4

  • Interleukin 4

  • Interleukin 5 (?)

  • Interleukin 6

  • Interleukin 8

  • Interleukin 13

  • Interleukin 17

  • CD3+CD8+

  • CD3+CD4+

  • CD4+IL4+

  • ERK 1/2 pathway

  • Eosinophils

  • Akt

  • PI3K-Akt

  • Syk

  • AP-1

  • PTEN

  • NF-κB

  • Cyclooxygenase – 1

  • Cyclooxygenase – 2

  • p-Smad2

  • p-Smad3

  • p-Smad4

  • EMT pathway

  • miR-34A pathway

  • GATA-3

  • 5AC mucine

  • ROS

  • c-RAF

  • JAK-STAT

  • NADH

  • 8-isoprostane

  • p47phox