Table 3.

Dose calculation of trifluridine/tipiracil according to BSA

Dose (mg/m2)	BSA (m2)	Dose in mg (BID)	Tablets per Dose (BID) 15 mg/6.14 mg	Tablets per Dose (BID) 20 mg/8.19 mg	Total daily dose (mg)
35	< 1.07	35	1	1	70
	1.07–1.22	40	0	2	80
	1.23–1.37	45	3	0	90
	1.38–1.52	50	2	1	100
	1.53–1.68	55	1	2	110
	1.69–1.83	60	0	3	120
	1.84–1.98	65	3	1	130
	1.99–2.14	70	2	2	140
	2.15–2.29	75	1	3	150
	≥ 2.30	80	0	4	160

BSA Body surface area. BID twice daily