Table 2.
Comparison of pathological features between the two groups of patientsa
| Tibetan group (n = 70) | Beijing group (n = 977) | P Value | |
|---|---|---|---|
| M0/M1 | 19/51 | 345/632 | 0.166 |
| E0/E1 | 36/34 | 597/380 | 0.11 |
| S0/S1 | 26/44 | 291/686 | 0.196 |
| T0/T1/T2 | 43/20/7 | 489/356/132 | 0.183 |
| C0/C1/C2b | 24/34/9 | 257/466/70 | 0.312 |
| IgA deposits | 2.5 [2.0, 3.0] | 3.0 [3.0, 3.5] | < 0.001 |
| IgG deposits | 0.0 [0.0, 0.0] | 0.0 [0.0, 0.0] | 0.087 |
| IgM deposits | 1.0 [0.0, 1.1] | 0.5 [0.0, 1.0] | 0.613 |
| C3 deposits | 1.0 [0.5, 2.0] | 2.5 [2.0, 3.0] | < 0.001 |
| C1q deposits | 0.0 [0.0, 0.0] | 0.0 [0.0, 0.0] | 0.779 |
M Mesangial hypercellularity, M0 < 50% of glomeruli showing mesangial hypercellularity, M1 > 50% of glomeruli showing mesangial hypercellularity, E Endocapillary hypercellularity, E0 No endocapillary hypercellularity, E1 Any glomeruli showing endocapillary hypercellularity, S Segmental glomerulosclerosis, S0 absent, S1 Present in any glomeruli, T Tubular atrophy/interstitial fibrosis, T0 0–25% of cortical area, T1 26–50% of cortical area, T2 > 50% of cortical area, C Cellular or fibro-cellular crescents, C0 absent, C1 0–25% of glomeruli, C2 ≥ 25% of glomeruli
aSome renal biopsy samples could not be scored by the MEST-C scoring system due to few glomeruli
bThere were no C classification in the early cases. Sixty-seven patients in the Tibetan group and 793 patients in the Beijing group had C scores