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. 2022 Jul 26;20:344. doi: 10.1186/s12951-022-01553-z

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 10 — A Structure of AQPO. B Schematic diagram illustration of AQPO NPs for cancer treatment. C Pictures of A549 tumor-bearing mice in different treatment groups on the 0 day and 16th day, respectively. D H&E and TUNEL staining of tumor sections of mice in different treatment groups. Reproduced with permission [177].

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