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. 2022 Jul 27;20:108. doi: 10.1186/s12958-022-00980-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Different states of dNK cells in URSA. A NK cells in the decidua were divided into 10 clusters (0 to 9) of characteristic cells according to differences in transcription. B The proportion of each NK-cell cluster in total cells was calculated, and the changes were compared between the URSA and control groups. C The molecular mechanism and pathway of NK Clusters 3, 4, and 1 were defined through KEGG enrichment analysis. D The differences in transcriptional levels between URSA and normal pregnant women were analysed in NK Clusters 3, 4, and 1. E The expression levels of differentially expressed genes in Clusters 3, 4, and 1 in URSA patients and normal pregnant women were compared by heatmap