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. 2022 Jul 22;6(14):4271–4282. doi: 10.1182/bloodadvances.2021005758

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Figure 8. — Glycan form by percent occupancy. *The percentage listed next to each glycan form represents how often this glycan was detected at that site. Glycan forms at each glycosylation site were previously evaluated by mass spectrometry. Glycan forms for rFVIII were isolated from Kogenate FS (baby hamster kidney-cell derived) (Bayer AG) and pdFVIII glycan forms from FVIIIenriched cryoprecipitate obtained from Shanghai Lai Shi Blood Products Co., Ltd (Shanghai, China). The experiments and analyses were performed at Georgia State University.¹⁰ †For N2118 site, variable occupancies of mannosylation of this site have been reported.^6,9,10 N-acetylglucosamine (GlcNAc); N-acetylhexosamine (HexNAc); Mannose (Man); Galactose (Gal); N-acetylneuraminic acid (Neu5Ac); L-Fucose; Ac, acetyl; S, sulfate.

Inline graphic — Glycan form by percent occupancy. *The percentage listed next to each glycan form represents how often this glycan was detected at that site. Glycan forms at each glycosylation site were previously evaluated by mass spectrometry. Glycan forms for rFVIII were isolated from Kogenate FS (baby hamster kidney-cell derived) (Bayer AG) and pdFVIII glycan forms from FVIIIenriched cryoprecipitate obtained from Shanghai Lai Shi Blood Products Co., Ltd (Shanghai, China). The experiments and analyses were performed at Georgia State University.¹⁰ †For N2118 site, variable occupancies of mannosylation of this site have been reported.^6,9,10 N-acetylglucosamine (GlcNAc); N-acetylhexosamine (HexNAc); Mannose (Man); Galactose (Gal); N-acetylneuraminic acid (Neu5Ac); L-Fucose; Ac, acetyl; S, sulfate.