Table 4.
Thoracic CT findings in different PcGVHD phenotypes
| Thoracic CT scan findings | Obstruction (N = 12) | Restriction (N = 67) | Mixed (N = 47) | Undefined (N = 40) | P | |
|---|---|---|---|---|---|---|
| Obstructive features* | Mosaic attenuation | 6 (50.0) | 34 (50.7) | 39 (82.9) | 29 (72.5) | .002 |
| Air-trapping | 6 (50.0) | 36 (53.7) | 37 (78.7) | 25 (62.5) | .040 | |
| Airway thickening | 4 (33.3) | 17 (25.4) | 29 (61.7) | 16 (40.0) | .001 | |
| Non-traction bronchiectasis | 2 (16.7) | 20 (29.9) | 24 (51.1) | 26 (65.0) | <.001 | |
| Cystic changes | 0 | 5 (7.5) | 2 (4.3) | 2 (5.0) | .712 | |
| emphysema | 0 | 2 (3.0) | 3 (6.4) | 0 | .328 | |
| Restrictive | GGO | 0 | 27 (40.3) | 31 (66.0) | 7 (17.5) | <.001 |
| features*,† | Consolidation | 0 | 8 (11.9) | 9 (19.1) | 1 (2.5) | .055 |
| Traction bronchiectasis | 0 | 23 (34.3) | 11 (23.4) | 3 (7.5) | .007 | |
| Lobar volume loss | 0 | 20 (29.9) | 9 (19.1) | 1 (2.5) | .003 | |
| Pleural abnormalities | 0 | 29 (43.3) | 16 (34.0) | 4 (10.0) | .002 | |
| Reticulation | 0 | 28 (41.8) | 19 (40.4) | 8 (40.0) | .050 | |
| PPFE | 0 | 3 (4.5) | 1 (2.1) | 1 (2.5) | .748 | |
| Normal* | 6 (50.0%) | 0 | 0 | 6 (15.0) | <.001 | |
PPFE, pleuroparenchymal fibroelastosis.
*
Number (percentage), χ2 test.
†
χ2 test between the RLS, M, and UD groups, without the BOS group.