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Combined (mixed) high grade prostatic adenocarcinoma and high-grade neuroendocrine carcinoma showing:
(A) Abrupt transition between the two components at 4x magnification
(B) Acinar adenocarcinoma component at 20x magnification highlighting intraluminal mucin, pale eosinophilic cytoplasm, and macronucleoli
(C) High-grade NE carcinoma component at 20x magnification highlighting basophilic cytoplasm, ‘salt and pepper’ nuclear chromatin, and 1-3 indistinct nucleoli
