Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 13;16:838692. doi: 10.3389/fnhum.2022.838692

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Tran, DiGiacomo, Born, Georgiadis and Zeineh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Relationship between QSM, β-amyloid, and longitudinal cognitive outcomes. (A) Heat map of average difference in QSM between β-amyloid positive subjects β-amyloid negative subjects. (B) Graphical representation of the impact of baseline QSM upon change of cognition, measured by cognitive composite scores of episodic memory (California Verbal Learning Test-delayed, Logical Memory Test-delayed, Rey Complex Figure Test-Long Delay). Annual rate of cognitive decline was calculated for each individual based on his or her trajectory of decline for the entire period they were included in the study. This is plotted against baseline QSM value. Baseline QSM in the hippocampus was negatively associated with annual rate of change in episodic memory in β-amyloid positive subjects (P = 9.2*10^{– 7}), and positively associated with rate of change in β-amyloid negative subjects (P = 0.014). Figure from Ayton et al. (2017b).