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[Preprint]. 2022 Jul 19:2022.07.18.500565. [Version 1] doi: 10.1101/2022.07.18.500565

Table2.

Top 10 of the First stable mutation in sars-cov2, including Orf3a to Orf9b

Locus mutant 1 mutant 2 mutant 3 mutant 4 mutant 5 mutant 6 mutant 7 mutant 8 mutant 9 mutant 10
Orf3a S(26)->L T(223)->I Q(57)->H E(239)->Q L(106)->F G(172)->V H(78)->Y S(253)->P D(155)->Y W(131)->C
Rate 43.1% 10.2% 5% 2.7% 2.1% 1.3% 1.4% 1.2% 0.8% 0.7%
Country France United States India England Brazil Germany Mexico
Continent Europe North America Asia Europe South America Europe North America
Date 2020-01-01 2020-06-27 2020-01-01 2020-03-09 2020-01-01
Orf6 D(61)->L K(48)->N E(46)->V P(57)->L T(21)->I I(33)->T W(27)->L R(20)->S Y(49)->H V(24)->F
Rate 9.4% 0.4% 0.2% 0.1% 0.07% 0.1% 0.09% 0.05% 0.04% 0.03%
Country England United States England Austria Venezuela India Netherlands India England
Continent Europe North America Europe South America Asia Europe Asia Europe
Date 2020-01-01 2020-04-06 2020-07-21 2020-01-01
Orf7a T(120)->I V(82)->A P(45)->L L(116)->F V(71)->I R(118)->G H(73)->Y P(34)->S P(84)->S T(14)->I
Rate 41.4% 41.1% 1.5% 0.9% 0.6% 0.2% 0.2% 0.1% 0.1% 0.2%
Country Netherlands France Saudi Arabia France United States India United States Wuhan Wales England
Continent Europe Asia Europe North America Asia North America Asia North America Europe
Date 2020-01-01 2020-02-17 2020-01-01 2020-03-20 2020-06-05 2020-01-01
Orf7b T(40)->I S(5)->L H(42)->Y A(43)->V S(31)->L L(4)->F A(15)->S L(32)->F M(1)->I C(41)->F
Rate 39.5% 0.1% 0.1% 0.04% 0.09% 0.07% 0.08% 0.07% 0.05% 0.05
Country France England France Guangdong Japan Gambia Greece United States England Thailand
Continent Europe Asia Africa Europe North America Europe Asia
Date 2020-01-01 2020-03-01 2020-01-28 2020-01-01
Orf8 S(24)->L E(92)->K T(11)->I A(65)->V F(120)->L S(67)->F A(51)->S I(121)->L V(100)->L L(84)->S
Rate 3.5% 2.6% 1.3% 0.5% 0.4% 0.5% 0.3% 0.4% 0.4% 0.4%
Country New Zealand England Armenia England Thailand Italy Gibraltar France England Wuhan
Continent Oceania Europe Asia Europe Asia Europe Asia
Date 2020-01-01 2019-12-30
Orf9b T(60)->A S(6)->C Q(77)->E P(10)->S R(32)->L S(50)->L V(15)->L G(38)->D P(3)->L H(9)->D
Rate 61.4% 4.2% 1.8% 0.8% 0.6% 0.8% 0.6% 0.4% 0.2% 0.1%
Country France Canada Brazil England Canada Russia England Foshan Niger
Continent Europe North America Europe Europe North America Europe Europe Asia Africa
Date 2020-01-01 2020-04-06 2020-03-20 2020-01-01 2020-03-01 2020-01-01 2020-01-22 2020-01-01
Orf9c G(50)->N V(49)->L L(52)->F L(67)->F E(51)->Q M(63)->T A(59)->V S(4)->L H(34)->Y V(40)->F
Rate 48.8% 2% 1.8% 1.8% 0.8% 0.1% 0.1% 0.1% 0.1% 0.1%
Country England United States England Austria United States England Greece
Continent Europe North America Europe North America Europe
Date 2020-01-01 2020-03-12 2020-03-27 2020-01-01