FIG 1.

Resistance to SARS-CoV-2 infection in selected bat cell lines. (A) Primary bat cells derived from wing tissues from four different species, as well as Vero E6 cells, were left uninfected (Mock) or were infected with SARS-CoV-2 at an MOI of 1 for 24 h and then analyzed via flow cytometry for viral spike (S) protein expression. (B) Representative dot plots of selected primary bat cells and Vero E6 cells. Data points represent three technical replicates. (C) Immortalized bat cell lines from four different species, as well as Caco-TC7 human intestine and A549 human lung epithelial cells, were left uninfected (Mock) or were infected with SARS-CoV-2 at an MOI of 1 for 24 h and then analyzed via flow cytometry for S expression. (D) Representative dot plots of selected immortalized cells. Data points represent three independent experiments with the exception of A549, FLN-ID, and FLN-R cells, where data points represent three technical replicates.