Table 2.
Multivariate analysis using the backward elimination method of conventional ultrasonography combined with contrast-enhanced ultrasonography before and after NAC according to the axillary lymph nodes
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR | p-value | OR | p- value | |
| Before NAC | ||||
| Lymph node medulla boundary: | - | - | - | - |
| Cortex of lymph node: | 32.0 (8.0–128.0) | p < 0.0001 | 9.7 (1.9–49.4) | p = 0.006 |
| Lymph node hilus: | - | - | - | - |
| Lymph node aspect ratio: | 9.6 (3.0–30.4) | p < 0.0001 | - | - |
| Contrast-enhanced ultrasonography way: | 24.8 (6.6–92.6) | p < 0.0001 | 7.4 (1.5–36.2) | p = 0.013 |
| Contrast-enhanced ultrasonography pattern: | - | - | - | - |
| After NAC | ||||
| Lymph node medulla boundary | 8.4 (2.1–33.5) | p = 0.003 | 11.7 (2.1–63.9) | p = 0.005 |
| Cortex of lymph node: | - | - | - | - |
| Lymph node hilus: | - | - | - | - |
| Lymph node aspect ratio: | 13.1 (3.3–52.4) | p < 0.0001 | 15.4 (3.0–77.0) | p = 0.001 |
| Contrast-enhanced ultrasonography way: | 3.5 (1.1–11.1) | p = 0.03 | 2.4 (1.1–5.3) | p = 0.231 |
| Contrast-enhanced ultrasonography pattern: | - | - | - | - |
NAC,neoadjuvant chemotherapy;OR,odds ratio.